Open Positions

Postdoctoral Position in Disease Modeling

Applications are invited for a two-year postdoctoral position in disease modeling, with Helen Moore, PhD in the Laboratory of Systems Medicine, University of Florida. Start date will be September 6, 2022 or later.

This is an opportunity to learn biology and advanced modeling methods, and to prepare for a faculty position in academia or for a modeling and simulation scientist position in the biopharma industry. Work on a project that can directly impact patients’ lives. Write manuscripts and contribute to grant proposals. Train with an award-winning teacher and mentor, who has spent 12 years in academia and 15 years in industry. Join a diverse group in a supportive department. Live in Gainesville, FL, a vibrant university town with a low cost of living and year-round access to nature and outdoor activities.

In this project, we will create and analyze a mathematical model for alpha-1 antitrypsin deficiency (AATD). AATD is a rare disease that is caused by an inherited genetic mutation. We will be closely collaborating with Mark Brantly, MD, who is a world expert in AATD and who initiated this project. Disease knowledge, data, and additional mentoring will be provided by Dr. Brantly and members of his lab. Project plans include literature searches, model development, calibration to data, model validation, sensitivity analysis, and optimal control. Promising model predictions will be tested by our experimental collaborators.

Preferred qualifications:

  • PhD in engineering, applied mathematics, mathematics, or similar fields by start date
  • experience with:
    • ODE modeling of an in-host disease
    • fitting model parameters to data
    • programming in MATLAB
    • writing manuscripts
  • ability to collaborate and communicate with scientists in other fields
  • interest in applications to biology and diseases
  • interest in learning model validation, sensitivity analysis, optimal control

Applications should include:

  • cover letter/email
  • curriculum vitae, including contact information for 3 references
  • any relevant peer-reviewed publications and posters

Review of completed applications will begin immediately and will continue until the position is filled. For more information or to apply for this position, send an email to

Women and members of underrepresented minority groups are especially encouraged to apply.

Faculty Positions in Computational Systems Medicine

The Department of Medicine at the University of Florida is expanding its research program in computational systems medicine with one position each at the tenured full, tenured associate, and tenure-track assistant professor level. These positions are research-focused, with modest teaching responsibilities. An internationally-recognized research program and demonstrated grant funding commensurate with seniority is expected.

All areas of research are being considered, with particular interest in the role of the immune system in a wide range of health conditions, such as respiratory diseases or cancer. Examples of current faculty research interests include multi-scale modeling of the immune response to respiratory infections, model-based control of microbial communities, ODE models of signaling pathways for tumor response to immunotherapy, and optimization of combination drug regimens.

We offer a highly collaborative research environment that closely integrates quantitative researchers with clinicians and experimentalists. The University of Florida is heavily engaged in a related initiative to build a strong research capability in artificial intelligence, including a partnership with Nvidia and the hire of 100 new faculty in this field. See this UF News item for more information.

The Laboratory for Systems Medicine is committed to increasing diversity, and especially welcomes applications from researchers who are members of underrepresented groups.

For more information, please contact Dr. Reinhard Laubenbacher,

Additional Openings

The newly established Laboratory for Systems Medicine at University of Florida Health is focused on computational and mathematical approaches to human health. We have several immediate openings for faculty positions at all ranks, in both the research and tenure tracks.

We are looking for scientists who work well in an interdisciplinary environment, have an outstanding record and who have a strong track record or promise of extramural funding. While expertise in respiratory diseases and immunology are of particular interest, all aspects of human health, the basic science underpinning it, systems biology approaches, and a focus on computational and data science methodology will be seriously considered.

We are committed to creating an environment that supports diversity, collaboration, and interdisciplinarity. For inquiries, please contact Dr. Reinhard Laubenbacher, We also have several research scientist and postdoctoral positions available for projects in computational systems biology, optimization, software development, bioinformatics, and biophysical modeling.