All Posts by

Cory Brunson

Dr. Sordo Vieira appointed an Affiliate Member of NITMB

Dr. Luis Sordo Vieira has been appointed an Affiliate Member of the National Institute for Theory and Mathematics in Biology. The NSF–Simons NITMB is a partnership between Northwestern University and the University of Chicago that integrates the disciplines of mathematics and biology to transform the practice of biological…

Dr. Laubenbacher awarded U.S. Army Research Office Grant

Dr. Reinhard Laubenbacher has received a new award from the U.S. Army Research Office to utilize the modular organization of complex biological systems to improve their analysis and control. An example of modularity in graphs. The left graph A can be simplified into graph B on the right by…

Multi-site cytokine predictors of primary graft dysfunction

Dr. Cory Brunson co-authored a research article with Dianna Nord, Carl Atkinson, and other colleagues just published in the Transplant International. Abstract:There is an urgent need to better understand the pathophysiology of primary graft dysfunction (PGD) to develop point-of-care methods predicting those at risk. We utilized a…

A Computational and Experimental Study of mTORC1 and SARS-CoV-2

Drs. Henrique Ribeiro and Reinhard Laubenbacher co-authored a research article with Achyudhan Kutuva, Felipe Lima, Matthew Schaller, and Borna Mehrad just published in the Bulletin of Mathematical Biology. Abstract:The mechanistic target of rapamycin complex 1 (mTORC1) has been implicated in coronavirus pathogenesis, yet its precise role in…

How AI Can Advance Mathematical Biology

Dr. Reinhard Laubenbacher co-authored a research article with Kobra Rabiei, Grzegorz A. Rempala, and Wenrui Hao just published in the Bulletin of Mathematical Biology. Abstract:Mathematical biology has long relied on mechanistic models, including ordinary and partial differential equations, stochastic systems, and agent-based models, to study biological processes…

Spatial modelling of NOTCH signalling

Dr. T. J. Sego co-authored a research article with Francois Chesnais and several others just published in npj Systems Biology and Applications. Abstract:Endothelial cells (ECs) are phenotypically heterogeneous to perform specialised functions across different organs and tissues. Although environmental inputs are considered key drivers, we previously observed…

Drs. Sego and Sordo Vieira awarded U.S. Army Research Office Grant

Drs. T.J. Sego and Luis Sordo Vieira have received a new award from the U.S. Army Research Office to develop approaches that integrate AI with mechanistic modeling. Drs. Sego and Sordo Vieira are Assistant Professors at the Laboratory for Systems Medicine. The project is titled “Integrating AI and…

Dr. Brunson awarded NIH/NHLBI training grant

Dr. Cory Brunson received a K25 Mentored Quantitative Research Career Development Award from the National Heart, Lung, and Blood Institute. Cory Brunson is an Assistant Professor in the Laboratory for Systems Medicine. Dr. Brunson is an Assistant Professor at the Laboratory for Systems Medicine. The project, titled “Machine…

T.J. Sego awarded NIH Replication Prize

Dr. T.J. Sego has been awarded the NIH Replication Prize (Track 1), “a competition to advance scientific research by collecting ideas and strategies to make important lines of biomedical research more replicable”. Dr. T.J. Sego is an Assistant Professor at the Laboratory for Systems Medicine. Dr. Sego’s…

Modeling cellular deformation and rearrangement

Dr. T. J. Sego co-authored a research article with Sharon B. Minsuk, David M. Umulis, Mary C. Mullins, and James A. Glazier just published open-access in npj Systems Biology and Applications. Abstract:Morphogenesis in early development involves complex and extreme deformations in response to intra- and intercellular forces.