Research

Mark Terasaki, Jason Cory Brunson, Kristina Suarez

Structure and development of glomerular capillaries

Topological modeling and simulation lend insight into the structure, development, function, and resilience of glomerular capillary networks.

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Yara Skaf, Osama Dasa, Jason Cory Brunson

Exploring Clinical Outcomes using Topological Data Analysis

In this project, we demonstrate how topological data analysis can be used to visualize, explore, and characterize large and complex biomedical data such as electronic health records.

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Luis Sordo Vieira, Carol A. Mathews

Predicting Populations At-Risk of Developing Pathological Hoarding

This study will identify risk-factors for developing troublesome hoarding by integrating and analyzing clinical interviews and a web-based registry of adults that includes various medical and cognitive questionnaires and neurocognitive

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Henrique de Assis L Ribeiro, Adam C Knapp, Luis L Fonseca

Multi-scale Modeling of the Immune Response to Aspergillus Fumigatus

Multi-scale agent-based modeling of the immune response and battle over iron in Aspergillus fumigatus infection

Multi-scale Modeling of the Immune Response to Aspergillus fumigatus

T.J. Sego

Quantitative Modeling of Recovery in the Human Pulmonary Alveolus

This project develops computational biophysics and biological models of lung epithelial recovery from insult.

Quantitative Modeling of Recovery in the Human Pulmonary Alveolus

Elena S. Dimitrova, Melissa L. Kemp, Daniel A. Cruz

Modeling of Emergent Patterning within Pluripotent Colonies

This project uses mathematical and computational tools to ascertain which modes of intercellular communication determine cell fate by studying both local interactions and emergent colony behaviors.

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Mahya Aghaee, Helen Moore

Mathematical Optimization of Combination Drug Regimens

Mathematical mechanistic modeling of diseases and drug effects can be used to predict regimens that produce optimal outcomes.

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Reinhard Laubenbacher, Borna Mehrad, Will Schroeder

Multiscale Model of Nutritional Immunity in Invasive Pulmonary Aspergillosis

We develop a whole-lung multiscale computational model to simulate the invasion of the human lungs by pathogens including spores of Aspergillus fumigatus.

Multiscale model of nutritional immunity in invasive pulmonary aspergillosis