Significant technological advances made in recent years have shepherded a dramatic increase in utilization of digital technologies for biomedicine– everything from the widespread use of electronic health records to… 

May 10, 2022 • 4:00 – 5:30

Cardiology Conference Room, Laboratory for Systems Medicine

Online registries offer many advantages for research, including the ability to efficiently assess large numbers of individuals and identify potential participants for clinical trials and genetic studies.

Aspergillus species are ubiquitous environmental moulds, with spores inhaled daily by most humans.

On April 9 at 9:00, Reinhard Laubenbacher will present a paper to the AMS Special Session on Current Advances in Computational Biomedicine at the Virtual 2022 Joint Mathematics Meetings.

On April 11 at 16:00, Reinhard Laubenbacher will present to the Texas A&M University Mathematics colloquium.

On April 12 at 18:00, Reinhard Laubenbacher will deliver the 2022 Sue Geller Undergraduate Lecture at Texas A&M University.

On Wednesday, May 18, Cory Brunson will give an oral presentation in a mini-symposium on Advances in Pre- and Post-Lung Transplant Care: From Selection to CLAD at the American Thoracic Society International Conference in San Francisco, CA.

On August 6–11, Cory Brunson will present at a Statistical Graphics section on graphing multivariate data at the Joint Statistical Meetings in Washington, DC.

Organizers: Daniel Alejandro Cruz, Margherita Maria Ferrari

Forum: Joint Mathematics Meetings

When: April 8, 2022

Adverse Childhood Experiences are stressful and traumatic events occurring before the age of eighteen shown to cause mental and physical health problems, including increased risk of obesity. Obesity remains an ongoing national challenge with no predicted solution. We examine…

Depriving microbes of iron is critical to host defense. Hemeproteins, the largest source of iron within vertebrates, are abundant in infected tissues in aspergillosis due to hemorrhage, but Aspergillus species have been…

Last year, a new product for the treatment of type-1 diabetes came on the market: a “digital twin” of the human pancreas. The patient is outfitted with a bloodstream sensor and an insulin pump. The sensor continuously sends data about insulin levels to a device that looks a bit like a cellphone and that runs a mathematical model of glucose metabolism.

Mathematical and computational models are a key technology in systems biology. Progress in the field depends on the replicability and reproducibility of their properties and behavior. For this, an essential requirement is a set of clear…

We introduce Steady Cell Phenotype, a browser based interface for the analysis of ternary biological networks. It includes tools for deterministically finding all steady states of a network…

As decisions in drug development increasingly rely on predictions from mechanistic systems models, assessing the predictive capability of such models is becoming more important. Several frameworks for the development of quantitative systems pharmacology (QSP) models have been proposed. In this paper…

Plasmodium knowlesi, a model malaria parasite, is responsible for a significant portion of zoonotic malaria cases in Southeast Asia and must be controlled to avoid disease severity and fatalities.

Optimization and control are important objectives across biology and biomedicine, and mathematical models are a key enabling technology. This paper reports a computational study of model-based multi-objective optimization in the setting of microbial ecology, using agent-based models. This modeling framework is well-suited to the field, but is not…

Aside from conducting research itself, communicating it to the broader mathematical sciences community—as well as the general public—is the most important task that a researcher must accomplish, for the sake of progress within both the mathematical sciences and one’s own career…

Helen Moore was Associate Director of Quantitative Clinical Pharmacology, Bristol-Myers Squibb in Princeton, New Jersey and recently joined UF as an Associate Professor in the Laboratory for Systems Medicine.

Reinhard Laubenbacher presented a talk at the weekly meeting of the multiscale modeling and viral pandemics working group. The title of his talk was “A modular computational framework for medical digital twins.”

This paper presents a modular software design that will help implement precision medicine in the form of medical digital twins which are computational models of disease processes calibrated to individual patients.

Reinhard Laubenbacher, co-authored an article, Using Digital Twins in Viral Infection,  in Science Magazine along with  James P. Sluka, and…

May 27th, 2021

AAA Annual Meeting, February 2021