Published
- Reinhard C. Laubenbacher. Medical ‘Digital Twins’ Will Lead the Way to Personalized Medicine. Scientific American. 14 May 2024. Article
- Walker M, Moore H, Ataya A, Pham A, Corris PA, Laubenbacher R, Bryant AJ. A perfectly imperfect engine: Utilizing the digital twin paradigm in pulmonary hypertension. Pulm Circ. 2024 Jun 25;14(2):e12392. doi: 10.1002/pul2.12392. PMID: 38933181; PMCID: PMC11199193.
- Laubenbacher R, Mehrad B, Shmulevich I, Trayanova N. Digital twins in medicine. Nat Comput Sci. 2024 Mar;4(3):184-191. doi: 10.1038/s43588-024-00607-6. Epub 2024 Mar 26. PMID: 38532133; PMCID: PMC11102043.
- Laubenbacher R, Adler F, An G, Castiglione F, Eubank S, Fonseca LL, Glazier J, Helikar T, Jett-Tilton M, Kirschner D, Macklin P, Mehrad B, Moore B, Pasour V, Shmulevich I, Smith A, Voigt I, Yankeelov TE and Ziemssen T (2024) Toward mechanistic medical digital twins: some use cases in immunology. Front. Digit. Health 6:1349595. doi: 10.3389/fdgth.2024.1349595
- Reinhard Laubenbacher, Fred Adler, Gary An, Filippo Castiglione, Stephen Eubank, Luis L. Fonseca, James Glazier, Tomas Helikar, Marti Jett-Tilton, Denise Kirschner, Paul Macklin, Borna Mehrad, Beth Moore, Virginia Pasour, Ilya Shmulevich, Amber Smith, Isabel Voigt, Thomas E. Yankeelov, Tjalf Ziemssen. Forum on immune digital twins: a meeting report. npj Systems Biology and Applications. 2024/02/16. 2056-7189. https://doi.org/10.1038/s41540-024-00345-5
- Laubenbacher R, Niarakis A, Helikar T, An G, Shapiro B, Malik-Sheriff RS, Sego TJ, Knapp A, Macklin P, Glazier JA. Building digital twins of the human immune system: toward a roadmap. npj Digit. Med. 2022 May 20;5,64. doi: 10.1038/s41746-022-00610-z.
- Masison J, Beezley J, Mei Y, Ribeiro HAL, Knapp AC, Sordo Vieira L, Adhikari B, Scindia Y, Grauer M, Helba B, Schroeder W, Mehrad B, Laubenbacher R. A modular computational framework for medical digital twins. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2024287118. doi: 10.1073/pnas.2024287118. PMID: 33972437; PMCID: PMC8157963.
- Laubenbacher R, Sluka JP, Glazier JA. Using digital twins in viral infection. Science. 2021 Mar 12;371(6534):1105-1106. doi: 10.1126/science.abf3370. PMID: 33707255; PMCID: PMC8170388.
Preprints
- Adam C. Knapp, Daniel A. Cruz, Borna Mehrad, Reinhard C. Laubenbacher. Personalizing computational models to construct medical digital twins. bioRxiv 2024.05.31.596692; doi: 10.1101/2024.05.31.596692
- Böttcher L, Fonseca LL, Laubenbacher RC. Control of Medical Digital Twins with Artificial Neural Networks. bioRxiv [Preprint]. 2024 Mar 20:2024.03.18.585589. doi: 10.1101/2024.03.18.585589. PMID: 38562787; PMCID: PMC10983973.
- Fonseca LL, Böttcher L, Mehrad B, Laubenbacher RC. Surrogate modeling and control of medical digital twins. ArXiv [Preprint]. 2024 May 20:arXiv:2402.05750v2. PMID: 38827450; PMCID: PMC11142319. doi: 10.48550/arXiv.2402.05750