Published by UF LSM
- R. Laubenbacher, P. Hatamizadeh, The promise of digital twins as a tool for personalized approaches in nephrology, Nature Reviews Nephrology, in press, 2025.
- F. Emmert-Streib, S. Parkkila, R. Laubenbacher, A. Mannermaa, L. Hood, O. Yli-Harja, The role of digital twins in P4 medicine: a paradigm for modern healthcare, Nature (npj) Systems Biology and Applications, in press, 2025.
- Anna Niarakis, Gary An, Luiz Ladeira, Noriko F. Hiroi, Athina Papadopoulou, Francis P. Crawley, Niloofar Nikaein, Laurence Calzone, Eirini Tsirvouli, Hasan Balci, Marina Esteban Medina, Lorenzo Veschini, Ozan Ozisik, Francesco Messina, Malvina Marku, Van Du T. Tran, Arnau Montagud, Nikola Schlosserova, Yashwanth Subbannayya, Martina Kutmon, Michael L. Blinov, Rahuman S Malik Sheriff, Robert Phair, Peter Hunter, Kristin Reiche, Jasmin Fisher, Liesbet Geris, Yaron Ilan, James A. Glazier, Philippe Moingeon, Reinhard Laubenbacher, Building Immune Digital Twins: An International and Transdisciplinary Community Effort, Immunoinformatics, in press, 2025.
- Knapp, AC, Cruz, DA, Mehrad, B, Laubenbacher, R., Ensemble Kalman filter methods for agent-based medical digital twins, PLoS Comp. Biol., in press, 2025.
- Knapp, A., Cruz, D.A., Mehrad, B., and Laubenbacher, R., Personalizing computational models to construct medical digital twins, J. Royal Soc. Interface 22:20250175, 2025
- Reinhard C. Laubenbacher. Medical ‘Digital Twins’ Will Lead the Way to Personalized Medicine. Scientific American. 14 May 2024. Article
- A. Niarakis, R. Laubenbacher, G. An, et al., Immune digital twins for complex human pathologies: applications, limitations, and challenges, Nature (npj) Systems Biology and Applications 10:141, 2024.
- Boettcher, L., Fonseca, L., Laubenbacher, R., Control of medical digital twins with artificial neural networks, Philosophical Transactions A, 383:20240228, 2025.
- Walker, M., Moore, H., Ataya, A., Pham, A., Corris, P., Wilkins, M., Laubenbacher, R., Bryant, A., A perfectly imperfect engine: utilizing the digital twin paradigm in pulmonary hypertension, Pulmonary Circulation, 14(2), e12392, 2024.
- Walker M, Moore H, Ataya A, Pham A, Corris PA, Laubenbacher R, Bryant AJ. A perfectly imperfect engine: Utilizing the digital twin paradigm in pulmonary hypertension. Pulm Circ. 2024 Jun 25;14(2):e12392. doi: 10.1002/pul2.12392. PMID: 38933181; PMCID: PMC11199193.
- Laubenbacher R, Mehrad B, Shmulevich I, Trayanova N. Digital twins in medicine. Nat Comput Sci. 2024 Mar;4(3):184-191. doi: 10.1038/s43588-024-00607-6. Epub 2024 Mar 26. PMID: 38532133; PMCID: PMC11102043.
- Laubenbacher R, Adler F, An G, Castiglione F, Eubank S, Fonseca LL, Glazier J, Helikar T, Jett-Tilton M, Kirschner D, Macklin P, Mehrad B, Moore B, Pasour V, Shmulevich I, Smith A, Voigt I, Yankeelov TE and Ziemssen T (2024) Toward mechanistic medical digital twins: some use cases in immunology. Front. Digit. Health 6:1349595. doi: 10.3389/fdgth.2024.1349595
- Reinhard Laubenbacher, Fred Adler, Gary An, Filippo Castiglione, Stephen Eubank, Luis L. Fonseca, James Glazier, Tomas Helikar, Marti Jett-Tilton, Denise Kirschner, Paul Macklin, Borna Mehrad, Beth Moore, Virginia Pasour, Ilya Shmulevich, Amber Smith, Isabel Voigt, Thomas E. Yankeelov, Tjalf Ziemssen. Forum on immune digital twins: a meeting report. npj Systems Biology and Applications. 2024/02/16. 2056-7189. https://doi.org/10.1038/s41540-024-00345-5
- Laubenbacher R, Niarakis A, Helikar T, An G, Shapiro B, Malik-Sheriff RS, Sego TJ, Knapp A, Macklin P, Glazier JA. Building digital twins of the human immune system: toward a roadmap. npj Digit. Med. 2022 May 20;5,64. doi: 10.1038/s41746-022-00610-z.
- Masison J, Beezley J, Mei Y, Ribeiro HAL, Knapp AC, Sordo Vieira L, Adhikari B, Scindia Y, Grauer M, Helba B, Schroeder W, Mehrad B, Laubenbacher R. A modular computational framework for medical digital twins. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2024287118. doi: 10.1073/pnas.2024287118. PMID: 33972437; PMCID: PMC8157963.
- Laubenbacher R, Sluka JP, Glazier JA. Using digital twins in viral infection. Science. 2021 Mar 12;371(6534):1105-1106. doi: 10.1126/science.abf3370. PMID: 33707255; PMCID: PMC8170388.
Preprints by UF LSM
- Fonseca LL, Böttcher L, Mehrad B, Laubenbacher RC. Surrogate modeling and control of medical digital twins. ArXiv [Preprint]. 2024 May 20:arXiv:2402.05750v2. PMID: 38827450; PMCID: PMC11142319. doi: 10.48550/arXiv.2402.05750