The relationships between hoarding disorder (HD) and other neurological and psychiatric disorders remain largely unknown. Although psychiatric burden in those with HD is high, less is known about neurological disorders.

Mahya Aghaee was awarded a Best Presentation prize at the 2022 American Conference on Pharmacometrics (ACoP13) Trainee Communication Challenge in Aurora, Colorado. All participants gave 5-minute presentations of their research without using any slides. Dr. Aghaee presented her work with Helen Moore on Multiple myeloma therapy optimization.

Luis Sordo Vieira has been accepted as a Regular Member of the Society of Biological Psychiatry (SOBP). Dr. Sordo Vieira was admitted based on his professional record and an endorsement from a current member.

December 12, 2022 • 4:30 – 6:00

On September 19, Luis L. Fonseca presented in a minisymposium on Boolean networks and related modeling frameworks at the 12th European Conference on Mathematical and Theoretical Biology (ECMTB 2022).

On August 8, Cory Brunson will present as part of an invited panel on New Developments in Graphing Multivariate Data at the Joint Statistical Meetings in Washington DC.

On July 11, Reinhard Laubenbacher will present at the 30th Conference on Intelligent Systems for Molecular Biology of the International Society for Computational Biology in Madison, WI.

In a special session on Expanding Tidyverse on June 23, Cory Brunson will discuss an open-source R package collection for TDA at the all-virtual useR! 2022.

Affiliation: Center For Pharmacometrics And Systems Pharmacology, University of Florida

Mentoring Undergraduate Researchers

This project seeks to develop a novel approach to the modular design of multi-scale models using virtual machines and a user friendly open-source platform. Availability of biomedical data sets across spatial and temporal scales makes it possible to calibrate complex models that capture integrated processes from the molecular to the whole organism level.

The project addresses an important biomedical problem: how to control biofilms formed by Candida albicans, a dimorphic fungus that is an important cause of both topical and systemic fungal infection in humans, in particular immunocompromised patients.

Multiscale modeling of disease requires the integration of data at various spatiotemporal scales. Extending these models is often challenged by complex computational implementations and interdependencies between components of the model. In this project, we are developing a computational blueprint so that computational models can be developed in a modular fashion, while minimizing interdependencies between model components.

Network analysis has gained popularity in systems medicine, though most applications have been “out of the box”. Cutting-edge network science draws from the rich history of graph theory and recent developments in statistical modeling and is aided by the speed, storage, and interoperability of computational resources. These distinctive research projects showcase the broader potential of network methods.