Welcome to the Laboratory for Systems Medicine

The newly established Laboratory for Systems Medicine at University of Florida Health is focused on computational and mathematical approaches to human health.

The Laboratory for Systems Medicine was established in 2020 as an initiative funded by the Department of Medicine and the Office of the President of UFHealth. The overarching focus is the development and application of mathematical and computational technology for the improvement of human health. Interests include multi-scale modeling and control of disease processes, systems biology, and computational immunology. We are highly collaborative, maintaining and seeking partnerships with clinical, basic science, computational, and private sector labs and entities. Our expertise includes the development of mechanistic and data-driven multi-scale models of disease-relevant processes, model-driven control and optimization problems, and cutting-edge data science methods applied to high-dimensional data from the molecular to the patient scale.



Systems medicine News

PUBLICATION

Forum on immune digital twins: a meeting report

Medical digital twins are computational models of human biology relevant to a given medical condition, which are tailored to an individual patient, thereby predicting the course of disease and individualized treatments, an important goal of personalized medicine. The immune system, which has a central role in many diseases, is highly heterogeneous between individuals, and thus poses a major challenge for this technology. In February 2023, an international group of experts convened for two days to discuss these challenges related to immune digital twins.

laubenbacher publication

UPCOMING/RECENT PRESENTATIONS

SEMINAR PRESENTATION

Determinants and Mediators of Racial-Ethnic Differences in Post–Lung Transplant Outcomes

Date: 1/11/24
Venue: UF Pulmonary Research Conference Seminar Series, Gainesville, FL
Presenter: Jason Cory Brunson

Cory Brunson

SEMINAR PRESENTATION

Treatment Optimization in Medical Digital Twins

Date: Oct 25, 2023
Venue:  UF Pulmonary Research Conference Seminar Series, Gainesville, FL

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SEMINAR PRESENTATION

How to Calculate an Optimal Drug Regimen

Date: Oct 18, 2023
Venue:  UF Pulmonary Research Conference Seminar Series, Gainesville, FL

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Upcoming Seminars

TUESDAY, JUNE 18, 2024

Austin Baird, Ph.D.

Whole Body Physiology Model to Simulate Respiratory Depression of Fentanyl and Associated Naloxone Reversal – A Model Informed Repeat Dosing Analysis

Austin Baird

Current Research Projects

we are hiring!

We are hiring!

The newly established Laboratory for Systems Medicine at University of Florida Health is focused on computational and mathematical approaches to human health.

Computational Research